The Santa Maria

Escape to Tranquil Luxury at Our Urban Hideaway, Where Every Detail Invites You to Unwind and Embrace the Essence of Relaxation.


The Santa Maria Hotel, located in Panama City, Panama, is a luxurious retreat that seamlessly blends modern elegance with the rich cultural heritage of the region. As a part of The Luxury Collection, this hotel offers guests an exquisite stay characterized by exceptional service, sophisticated accommodations, and a range of premium amenities.


Accommodation: The Santa Maria Hotel features opulent rooms and suites designed with contemporary decor and equipped with plush bedding, flat-screen TVs, spacious work desks, and stunning city or golf course views. The bathrooms are adorned with marble finishes and offer luxurious toiletries.

Dining: The hotel boasts several dining options, including a signature restaurant serving gourmet Panamanian and international cuisine, a stylish bar offering a variety of cocktails and fine wines, and a café perfect for a quick bite or coffee.

Wellness and Recreation:

— Spa: Guests can indulge in a range of rejuvenating treatments and therapies at the hotel’s spa, which includes massage rooms, a sauna, and a steam room.

— Fitness Center: A state-of-the-art fitness center is available for those looking to maintain their workout routine, featuring modern equipment and personal      training services.

— Golf: The Santa Maria Hotel is renowned for its 18-hole, Nicklaus Design golf course, offering a challenging yet scenic experience for golf enthusiasts.

Swimming Pool: 

The outdoor infinity pool provides a perfect place to relax, with comfortable loungers, poolside service, and panoramic views of the surrounding greenery.

Event Spaces: The hotel features versatile meeting and event spaces, including elegant ballrooms and well-equipped conference rooms, ideal for weddings, business meetings, and other special events.

Nearby Attractions

Casco Viejo: Just a short drive from the hotel, Casco Viejo is the historic district of Panama City, known for its charming cobblestone streets, colonial architecture, vibrant nightlife, and cultural landmarks such as the Metropolitan Cathedral and the National Theater.

Panama Canal: One of the world’s most famous engineering marvels, the Panama Canal, is a must-visit attraction. The Miraflores Visitor Center offers an insightful look into the canal’s history and operations, along with the chance to watch ships transit the locks.

Amador Causeway: This scenic stretch connects the mainland to four small islands and offers stunning views of the Panama City skyline and the Pacific Ocean. It's perfect for walking, cycling, or enjoying a meal at one of the many waterfront restaurants.

Biomuseo: Designed by renowned architect Frank Gehry, the Biomuseo is an interactive museum that explores the natural history of Panama and its pivotal role in the world's biodiversity.

Shopping: The hotel is conveniently located near several upscale shopping destinations, including the Multiplaza Pacific Mall and the Soho Mall, where guests can find a wide array of international brands, designer boutiques, and dining options.

Metropolitan Natural Park: For those who enjoy nature, this urban rainforest park offers hiking trails, wildlife spotting, and breathtaking views of the city skyline from its various lookout points.

The Santa Maria Hotel in Panama City provides an unparalleled blend of luxury, comfort, and convenience, making it an ideal destination for both leisure and business travelers.


Ready to jet set?  Book your adventure now and embark on your dream journey!

Experience Panama like never before.